ea0081ep584 | Endocrine-Related Cancer | ECE2022
Agraz-Doblas Antonio
, Blazquez-Encinas Ricardo
, Garcia Vioque Victor
, Alcala Nicolas
, Sexton Alexandra
, Trinidad Moreno Montilla Maria
, Alors-Perez Emilia
, salamanca jimenez pilar
, Foll Matthieu
, Cuesta Lynnette Ferna nez
, Ibanez Costa Alejandro
, P. Castano Justo
Lung neuroendocrine neoplasms (LungNENs) comprise a diverse group of rare tumors with a commonly difficult and late diagnosis, which often require complex management and treatment. The most frequently mutated genes in LungNENs have recently been identified, including known components of the chromatin-regulating pathways such as MEN1, PSIP1 and ARID1A, which are the subject of ongoing detailed studies. In contrast, other key regulatory mechanisms, par...